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Such indignation has far outlived the Poor Law of 1834, against which it was directed.
A last-minute £1m donation from the Express newspaper owner Richard Desmond clearly failed to make a difference in the areas to which it was directed.
It wasn't very fun anymore by the time we went and shot it, and I think you can feel that in the over mannered way in which it was directed.
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The RNase however becomes toxic when internalised in ErbB2-positive tumour cells, to which it is directed through its fusion with Erbicin.
From a psychological point of view, her valuation activity has changed not just in the object toward which it is directed, but in its cognitive character: it embodies an articulate understanding of what she is going after, which reflects her appraisals of its merits.
Also, one may plausibly try to find an affinity between externalist views in analytic philosophy, and the later phenomenologists' rejection of Husserl's reduction, based on their doubt that we can prise consciousness off from the world at which it is directed, and study its 'intentional essence' in solipsistic isolation.
But the exact mechanics of communication, the precise purpose to which it is put, and the identities of the powers to which it is directed — these are as various, mutable and mysterious as the art itself.
The distinguishing characteristic of the truly free will is found in the object towards which it is directed (PE 155).
According to Stumpf, the heart of Spinoza's parallelism rests on the distinction between act (or mental state) and the immanent object towards which it is directed.
He points out that inner perception must not be mixed up with inner observation, i.e., it must not be conceived as a full-fledged act that accompanies another mental act towards which it is directed.
If nothing has its nature intrinsically and independently there can also be no argument for a particular thesis that by its very nature establishes its conclusion independent of the context in which it is made and independent of the audience towards which it is directed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com