Instead, helix 12 is positioned over the hydrophobic cleft between helices 3, 4, and 5, in which position it precludes completely interaction of coactivators with this surface of the receptor.
Ordinal logistic regression is the model of choice when the dependent variable is ordinal in nature, but the Proportional Odds Assumption (or parallel regression assumption) with which it operates often precludes its use [ 38].
Citigroup declines to comment on the transaction, but says that it is "uncomfortable" with such deals, which, it claims, are precluded by new policies adopted last August.
In reality becoming Pope is just as cutthroat and political a move as becoming a President; men work towards it their entire careers and must be filled with ambition to achieve it -- which hardly precludes a desire to do good but is a fact nonetheless.
The Roadster's range on a full charge is 244 miles in the E.P.A.'s combined city-highway calculation, which precludes it from being a long-haul road-trip car.
We observed that, as reported previously, fibroblasts express CD68, which precludes it as a marker to discriminate fibroblasts from macrophages and fibrocytes [51] [54].
F508del-CFTR is associated with defective traffic (Class II) which precludes it from reaching the cell surface [reviewed in (Amaral, 2004)].
Which factors preclude it from being done more often?
It has reasonably high sensitivity to low temperature, which precludes its survival in waters where temperature falls below 10 ºC.
It is cross-sectional, which precludes validation of causative associations, and from a single centre, which affects generalizability of the results.
Quantile regression is robust in dealing with skewed distributions and outliers, which makes it especially suited to our approach, which precludes checking error distributions and removing outliers.
