Sentence examples for which is disordered from inspiring English sources

This region, which is disordered in the X-ray models where an abasic site-containing DNA is bound to Fpg, interacts tightly with the 8-oxoG which appears to be confined within the enzyme.

The part of the C-terminus of both arrestin-2 and -3 between the C-domain and β-strand XX (Fig. 1), which is disordered and never resolved in crystal structures, contains both the major (Goodman et al., 1996) and minor (in arrestin-2) (Kang et al., 2009) clathrin-binding sites (Fig. 2A).

Since there is a 22-residue linker between the FN4 and FN5 domains, which is disordered in the crystal structure and can potentially stretch somewhere around 80 Å, we cannot authenticate which FN4 domain is linked to which FN5 domain to form one molecule.

Therefore, the inner cavity of 2 a-Br is now almost empty and only occupied by one solvent molecule CH2Cl2, which is disordered over 32 positions.

An interesting feature in the PI3K structures is the activation loop, a significant part of which is disordered and, therefore, not visible in the electron density maps.

Indeed, even in the GTPase domain, the structures are completely superimposable, with the exception of the switch I region, which is disordered in aSelB [ 27].

There are 6.5 lattice water molecules per formula unit, some of which are disordered.

However, upon transplantation into living organisms, undifferentiated hESCs can spontaneously differentiate into rapidly proliferating teratomas, which are disordered amalgams of all three germs layers [2], [3].

The final CusC model consists of the complete mature sequence, with the exception of residues 21 31 within the equatorial domain, which are disordered (Fig. 1A) [21A.

Such regions, which are disordered in the bound form, are termed fuzzy.

The final model did not include residues 1 and 31-43 of BCL-XL, which are disordered in the crystal.