Statistical heterogeneity was assessed using the I statistic, which was assessable in two of the comparisons, as the majority of treatments had only been tested in phase III trials once.
The 49 patients underwent a total of 216 treatment cycles (median, 4 cycles), 212 of which were assessable for toxicity.
The primary outcome that we used was whether patients were sexually active or not, which is easily assessable, though does not capture all relevant domains of sexual function.
However, many patients who pass WBD protocols do not exhibit diabetes insipidus and retain residual neurohormonal regulation, which is readily assessable at the bedside; according to the most stringent definition of 'critical', this does not indicate mere activity but organized functioning.
It is suggested that five-carbon linker analogues containing a cyclohexane ring which are synthetically assessable may be pharmacologically important.
The contributing effects of other treatments (such as maintenance of haemoglobin levels), which was not assessable in the current dataset, cannot be excluded.
Similarly, subgroups of DCIS were analysed in accordance with the Van Nuys Pathologic Classification (Table 1), which was not assessable in six patients [ 41].
Similarly, subgroups of DCIS were analysed in accordance with the Van Nuys Pathologic Classification (VNPC) (Table 1), which was not assessable in five patients [ 32].
Native coronary segments (including stented segments) and grafts, which were not assessable because of severe calcification and motion artefacts, were regarded as severe stenoses.
The three components of the LCL could be visualised in all specimens and normal volunteers with the exception of the proximal portion of one specimen, which was not assessable due to a large calcification, located in the overlying extensor tendons.
