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This is supported by the known binding mode of acetazolamide, which interacts in the same pocket with an ethyl group.
Pur-alpha is a highly conserved protein, which interacts in a sequence-specific manner with single-stranded DNA and RNA.
The mutant RNA expression is associated with the activation of apoptosis and the functional inactivation of the hnRNP K protein, which interacts in situ with AUUCU repeat expansions.
This is an interesting feature as IL6 can also bind to a soluble IL6R (sIL6R) variant, which interacts in an IL6R agonistic manner with gp130, thus, enabling the stimulation of cells lacking endogenous IL6R [ 142].
These include BICDR-1, which interacts in lysates and by yeast two-hybrid at the C-terminus of KIF1C (Schlager et al., 2010), and myosin IIA, which in lysates, interacts in the region before the C-terminus (residues 713 811; Kopp et al., 2006).
In CYP720B4, a conserved W box motif (TTGACC), which interacts in Arabidopsis with members of the WRKY transcription factor family to mediate responses to wounding or pathogen responses [ 39], is located at position -1,129 relative to the ATG of CYP720B4 on PGB04.
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These are the neuronal transmembrane protein Neurexin IV (Nrx IV) and the membrane-anchored MG protein Wrapper, both of which interact in trans to mediate neuron-glial interactions and ensheathment of commissural axons.
Genes are the instructions for the production of proteins, which interact in complex ways to carry out functions in the body.
"The current system of benefits provides targeted support to meet specific needs, but the net effect is a complex array of benefits which interact in complicated ways, creating perverse incentives and penalties, confusion and administrative cost.
This paradigm holds that everything can be reduced to the tiniest particles which interact in a clockwork-like fashion.
The reed bed system has simple components, which interact in a complex manner to produce an ideal medium for wastewater treatment (Adcock et al. 1999).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com