Several animal and in vitro studies provide insights into possible mechanisms by which tumours initially become resistant to endocrine therapy.
The orderly development of an organism depends on a process called cell determination, in which initially identical cells become committed to different pathways of development.
Skills which initially seem superfluous become vital later on in the game, when Takkar has to take on vast hordes of enemies (and the odd boss) with just his trusty beast at hand.
The stock, which peaked at $57.25 in early 1998, is now trading about where it was when Mr. Trani initially became chief executive.
Belle and his work initially became known through French television in the late 1990s and later through videos posted on YouTube , which have attracted hundreds of millions of viewers.
In 2003, Mr. Derner, an airline dispatcher, started a Web site that became nycaviation.com, which initially served as an informational hub for fellow plane spotters, who shared photographs of jets and tips on the best vantages from which to watch for them.
Far too quickly the gang, which initially provided sanctuary and protection, becomes the very tool which perpetuates a more violent response.
The membrane transport models mostly result in the dependence of the permeability coefficient on the partition coefficient, which initially linearly increases and later becomes stable, such as, e.g., the black curve in Figure 22.
This model is supported by electroencephalography studies of the Bereitshaftspotential, which initially develops bilaterally and only becomes lateralized a few hundred milliseconds prior to movement onset (Shibasaki and Nagae 1984; Kristeva et al. 1991).
The semitendinosus tendon, which initially had no vessels after grafting, gradually became vascularized, expecially after 40 days after surgery.
