Sentence examples for which in cells from inspiring English sources

Importantly, studies applying direct neuronal conversion to both neonatal and adult human somatic cells demonstrated clearly that passive membrane properties of iN cells derived from adult human tissue remain highly immature at time points at which iN cells derived from neonatal human tissue have already matured significantly [ 97, 99, 101, 119].

The binding triggers the β2AR to change shape and release a "G" protein, which in cells binds to the inside end of the receptor.

Support for this idea was available in the original HBM publication describing the LRP5 activating mutation, which in cells eliminated the inhibitory actions of DKK1.

Mammalian GAPD-1 is a well-studied protein, a high concentration of which in cells (5-15% of all cytoplasmic proteins) confirms its functional significance.

Accordingly, activity assays were performed with GST-tagged Parkin, and while some mutants (K161N, R234Q) showed similar autoubiquitination to wild-type Parkin, interface mutants M192A and F463A on either side of the UPD RING2 interface, and linker helix mutation A398T showed increased autoubiquitination activity, which in cells may lead to increased turnover.

An example of gene identification is TAFA1, the significance of which in cell transformation was found by array-CGH and was verified extensively with other methods [ 93].

DNA is tightly packed in chromatin, which in eukaryotic cells consists of highly organized nucleosomes.

This stimulates aerobic glycolysis, which in cancer cells is known as the Warburg phenotype [ 33, 34].

He added four genes to skin cells which transformed them into stem cells, which in turn could become specialised cells.

Taken together, PTH acts on stromal cells which, in turn, signal to hematopoietic cells.

PDGF is a multiple biofunctional growth factor, which participates in cell migration, proliferation, chemotaxis, and vascularization.