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We also find that every linker position contributes to function, which has twofold implications.
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The emergence of two 8-barrel enzymes involved in histidine biosynthesis, each of which has a twofold symmetric structure, has been proposed to be a consequence of tandem duplication and fusion of a 4-half-barrel.
It takes a set of traces and applies an alignment procedure called binning [ 51- 54], which has a twofold effect.
L902,688, which has approximately twofold greater affinity than PGE2 for EP4 receptors (Supporting Information Table S4), stimulated a concentration-dependent (pEC50 = 7.76 ± 0.11) accumulation of cAMP that was only 32±2%2% (n = 3) of that evoked by a maximally effective concentration of PGE2.
Because of a short in vivo half-life of DAB486IL-2, efforto to reengineer the molecule were undertaken, leading to the DAB389IL-2 construct, which had a twofold to threefold higher Kd than DAB486IL-2 and a longer half-life, resulting in a tenfold increase in potency.
It has twofold implications.
The paper has twofold goals.
Note the problem formulated in (15)–(18) has twofold tasks.
This finding has twofold relevance.
Byron and Wordsworth are enshrined in noble and scholarly editions, while the text of Shelley has been purified in a masterly fashion from the perplexing corruptions which had crept in to mar his twofold harmony of thought and sound.
Chemistry had twofold reasons for adopting this principle.
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CEO of Professional Science Editing for Scientists @ prosciediting.com