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This permitted an extensive antiviral analysis, which found potent activity toward vaccinia, cowpox, and monkeypox viruses.
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In the five years since The Huffington Post and YouTube were launched, aspiring filmmakers, bloggers, and citizen journalists have found potent new outlets through which they can express themselves.
Pyrrolyl-propionic and butyric-acid derivatives 1 and 2 were synthesized in order to study the effect of the variation of the methylene chain in comparison to the previously reported pyrrolyl-acetic acid compound I, which was found as potent aldose reductase inhibitor, while the pyrrolyl-tetrazole derivatives 3 5 were prepared as a non-classical bioisosteres of a carboxylic acid moiety.
"She is very mentally dexterous, and she is also full of rage, and it is also a real expression of female rage, which I find quite potent.
Our efforts led to compound 10 which was found to have potent dual activity (HDAC6 IC50 = 0.0356 μM and AR binding IC50 = <0.03 μM).
We herein report the design and synthesis of a novel series of thiophene- and furan-based aminoquinoline derivatives which were found to be potent antimalarials and inhibitors of β-hematin polymerization.
Another study done on jungle honey obtained from the tropical forest of Nigeria showed that this type of honey possessed chemotactic activity for neutrophils, which were found to possess potent antitumour activity mediated by reactive oxygen species (ROS) [ 45].
A drug discovery programme directed at phosphoinositide 3 kinase (Hayakawa et al, 2006) identified a pyridofuropyrimidine compound, YM201636 (Fig 1A), which was found to have potent in vitro inhibitory activity against PIKfyve, with a half-maximal inhibitory concentration (IC50) of 33 nM (Table 1).
An initial library of 32 analogs was synthesized, two of which were found to be more potent than the reported activity for a 12 amino acid peptide antagonist.
Furthermore, it was used for the determination of the inhibitory potency of a newly synthesized chloromethyl ketone derivative, Cbz-Phe-Glu(CMK -Val-Lys-Val-Ile-Gly-NH2, whiCMK -Val-Lys-Val-Ile-Gly-NH2irreversible inhibitor of FXIII-A2∗.
Using the lead compound DUO3, which was found to be a potent inhibitor of the AChE and butyrylcholinesterase (BuChE) as well as an inhibitor of the formation of the amyloid (Aβ) plaque, new non-permanently positively charged derivatives were synthesized and biologically characterized.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com