A state feedback stabilization controller design method is proposed and a basin of attraction depending on the singular perturbation parameter is constructed, which facilitates the formulation of the convex optimization problem for maximizing the basin of attraction of SPSs.
Additionally, a double-auxotrophic strain that allows multiple genomic manipulations was constructed, which facilitates metabolic engineering purposes in T. reesei.
Many of the RITE cassettes contain unique restriction sites between the different elements, which facilitates modification of the constructs for other applications.
A genome-wide physical map of the B. rapa genome was constructed by high-information-content fingerprinting (HICF) [ 44], which facilitates improved physical map construction in both throughput and quality by exploiting the fluorescence-labeled finger-printing approach.
For bulky prostate tumours, sufficient tissue may be present to construct tissue microarrays which facilitates high throughput analysis [ 14, 15]; however, in intermediate risk localised prostate tumours this approach has recently been shown to be unfeasible due to inadequate numbers of tumour cells [ 16].
Given the overlapping nature of information content in gene sequences (DNA, RNA, and protein level) we endeavored to create a database and software tool called Gene Composer which facilitates the design of protein constructs, guided by 2D and 3D information, while the corresponding nucleic acid sequences are engineered for both codon usage and other desired sequence features.
An important aspect of DNA nanotechnology is the ability to engage molecular recognition and intrinsically define structural features with nanometer precision, which facilitates the employment of useful strategies to construct functionalized DNA nanostructures for their use in biomedical applications.
To address this issue, we have constructed a "system design space" which facilitates the quantitative comparison of wild-type and variants for the redox cycle.
With the goal of improving yield and success rates of heterologous protein production for structural studies, we have developed Gene Composer, a database software package which facilitates the information-rich design of protein constructs and their codon engineered synthetic gene sequences.
To improve efficiency in high throughput protein structure determination, we have developed a database software package, Gene Composer, which facilitates the information-rich design of protein constructs and their codon engineered synthetic gene sequences.
