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Our data suggest that the methods, which enable specific cluster motions, such as CMC, should be used for a more realistic description of protein folding.
Can circulating biomarkers, which enable specific diagnosis of the disorder or guide TH therapy, including preventing unwanted toxicity in TRβ-expressing tissues, be developed?
No less than 18 different sigma factors were identified in C. metallidurans CH34, which enable specific binding of RNA polymerase to promoters, and are activated in response to different environmental changes [ 8].
We have also seen remarkable technological advances in gene transfer and cell manipulation and culture, which enable specific engineering of both human stem cells and terminally differentiated cell populations for many applications.
These groups enhance the polymer polarity and wettability and promote the adsorption of cell adhesion-mediating molecules in appropriate geometrical conformations, which enable specific amino acid sequences (e.g., RGD) in these molecules to be reached by cell adhesion receptors.
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Generic NICEON technology was compatible with a variety of constitutive viral and mammalian housekeeping promoters, each of which enabled specific induced, repressed, adjusted and reversible transgene expression profiles in Chinese hamster ovary (CHO-K1), baby hamster kidney (BHK-21) as well as in human fibrosarcoma HT-10800) cells.
In order to isolate the Hcrt neurons, the transgenic hcrt:EGFP zebrafish (Appelbaum et al., 2009), which enables specific visualization and manipulation of the entire population of Hcrt neurons (16- 20 16- 20per larva), was used.
Indeed, thalamocortical axon pathfinding has so far been mostly examined by either axonal tracing using lipophilic tracers or immunostaining, neither of which enable a specific labeling of the entire axonal projection.
More specific Neighbourhood Development Orders can also be produced by these local groups which will enable specific types of development (such as extensions) to happen without the need for applying planning permission.
Techniques to aid TMS coil placement may improve the treatment response, such as stereotactic systems which can enable specific regions to be targeted on the basis of an individual patient's structural magnetic resonance imaging (MRI) scan.
These obstacles might be overcome by 'molecular pathological epidemiology', which enable pathway-specific epidemiologic study (Ogino et al, 2011, 2013).
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