Sentence examples for which efficacious from inspiring English sources

The remaining one-third were typically larger (>200 subjects) phase II or III trials, but, disappointingly, only fewer than one-half of these administered neuroprotective therapy within the 4 6 h therapeutic window within which efficacious neuroprotection is considered to be achievable.

The gathered information not only provides a clearer picture for the specificity, functionality and complexity of the IFN system and its effector mechanisms in the control of HCV infection, but also helps to identify novel cellular targets against which efficacious therapeutic strategies can be developed.

Therefore, further deciphering which ISGs and/or IEGs are induced by IFNs upon HCV infection and the specificity and action of these ISGs and other cellular immune regulators on HCV replication will not only provide insights into how IFN functions to obstruct HCV replication but will also reveal novel cellular targets against which effective and efficacious anti-HCV therapeutics can be developed.

The search for safe and efficacious agents for use in inflammatory conditions is ongoing with the objective to find new drugs which are efficacious but with few side effects.

The search for safe and efficacious agents for use in the medical oncology field is ongoing with the objective being to find new drugs which are efficacious but with fewer side effects.

More recently, diverse prophylactic drugs, which are efficacious for the prophylactic treatment of MwA and MwoA, have been shown to experimentally suppress SD susceptibility.

In conclusion, telephone-based guided self-help is an acceptable minimal intervention which is efficacious in reducing fatigue in adolescents with CFS.

Remarkably, we obtained compounds with enzyme inhibition values (IC50) as low as 2 nM, which were efficacious against wild type and multidrug-resistant strains of T. brucei and T. congolense.

In this study, we determined the effect of new phenylalanine-derived (Z -5-arylmethylidene Z -5-arylmethylidene Z -5-arylmethylidene Mrhodaninese activity of the twhichpe II bareefficacioussomeragainstNA gyrase and topoisoMRSAse IV (Tono IV).

Montelukast, a newer leukotriene antagonist, which is efficacious and safe in patients with asthma 6 years of age and older, has not been reported as therapy for atopic dermatitis.

BMS-189664 (3) is identified as a potent, selective, and orally active reversible inhibitor of human α-thrombin which is efficacious in vivo in a mouse lethality model, and at inhibiting both arterial and venous thrombosis in cynomolgus monkey models.