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Validation should be performed within a sufficiently defined patient population (indication) and comparable interventions (pharmaceuticals with similar mode of activity), which drastically limits transferability.
Cartilage is unlike any other tissues, its structure is designed purely for load-bearing and thus it is avascular and contains little cellular composition, which drastically limits self-repair ability.
Now if we assume no out-and-out malicious intent, we must conclude that FaceApp's team suffers from a lack of diversity, and thus exhibits low empathy for ethnicities outside its caucasian baseline — all of which drastically limits its perspective, causing the team's product choices to bounce them from one offensive controversy to another.
Wedding dresses take six to eight months to be delivered, so if you wait too long, you'll be forced to pull from samples, which drastically limits your selection.
Another study revealed that the country has the fewest anesthesia providers per capita -- one for every five million people -- which drastically limits its ability to deliver surgical care.
The unavailability of the whole genome sequence of the complex allotetraploid B. napus makes it still a challenge to determine genetic differences among individuals, which drastically limits this economically important oil crop to benefit from NGS technology.
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As part of a "stabilisation" force, troops were expected to act more like policemen in camouflage, which "drastically limited" their scope for action, says Mr Kress.
The AWU initially campaigned against price controls, which drastically limited the incomes of market women, and for fair treatment of market women by the government.
In 1983, parents at Woodside Elementary School, which is surrounded by some of the Valley's wealthiest tech families, started a foundation in order to offset budget cuts resulting from the enactment of Proposition 13, in 1978, which drastically limited California property taxes.
Very importantly, virtual tumor T4 satisfies concurrently a considerable number of constraints which drastically limit the value range of the critical model parameters implicated in tumor response to therapy (e.g. Psym, Psleep).
powerful emissions need a heavy power supply which can drastically limit the efficiency of autonomous monitoring systems, thereby causing drastic harm to marine mammals and disturbing their behavior.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com