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To define the regulation of Osx transactivation in osteoblast differentiation, we stably transfected Flag HA Osx into the mouse C2Cl2 line, which differentiates into osteoblasts on BMP-2 addition.

These cells of the iris, which normally contain pigment granules, lose their colour, proliferate rapidly, and collect into a spherical mass which differentiates into a new lens.

We confirmed these observations in Caco-2 cells, a human colon carcinoma cell line which differentiates into a polarized enterocyte-like cell type and endogenously expresses meprinα [14].

Inner cells give rise to the inner cell mass (ICM) which differentiates into embryonic lineages, while outer cells give rise to the trophectoderm (TE) which gives rise extraembryonic tissues [1].

The murine KS483 cell line is a mesenchymal precursor cell line, which differentiates into mature mineralizing osteoblasts during a three-week culture period, when cultured under osteogenesis inducing conditions.

Chondrogenesis is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondrocytes and begins secreting the molecules that form the ECM.

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Differentiated fetal neural stem cells which differentiate into 10 20% neurons (astrocytes make up the remaining percentage) were used as a positive control for RT PCR and qRT PCR for MECP2 (kind gift from P. Dirks).

In brief, Delta-1 is expressed in single cells, which differentiate into neurons, and it impairs the differentiation of neighbouring cells by activating NOTCH signalling.

Here, we have shown that hypoxic priming enhanced differentiation of EBs into meso-endodermal cells, which differentiated into vascular-lineage cells more efficiently than normoxic EBs did.

Here, we demonstrated that hypoxic priming enhanced differentiation of EBs into meso-endodermal cells, which differentiated into vascular-lineage cells more efficiently than normoxic EBs did.

'Classically' activated macrophages are monocytes stimulated with IFNγ, alone or in combination with IL-12 and IL-23, which differentiate into M1-polarised cells that induce the differentiation of Th1 type responses.

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