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Here, we demonstrated that hypoxic priming enhanced differentiation of EBs into meso-endodermal cells, which differentiated into vascular-lineage cells more efficiently than normoxic EBs did.
Here, we have shown that hypoxic priming enhanced differentiation of EBs into meso-endodermal cells, which differentiated into vascular-lineage cells more efficiently than normoxic EBs did.
SDF-1α effectively recruited endothelial progenitor cells (EPCs) to the luminal surface of the grafts, which differentiated into endothelial cells (ECs) and accelerated endothelialization.
Furthermore, we demonstrated that scattered Sox10-expressing cells existed around the developing inner ear, some of which differentiated into pigmented melanocytes in the stria vascularis, suggesting that they were neural crest cells.
It formed an extensively branched substrate mycelium and aerial hyphae which differentiated into spore chains.
GCLRP was associated with an increased percentage of precursors of dendritic cells in the blood (P = 0.003), which differentiated into patrolling macrophages in tumoral (P = 0.001) and peritumoral areas (P = 0.04), rather than into dendritic cells, as in control animals.
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Differentiated fetal neural stem cells which differentiate into 10 20% neurons (astrocytes make up the remaining percentage) were used as a positive control for RT PCR and qRT PCR for MECP2 (kind gift from P. Dirks).
In brief, Delta-1 is expressed in single cells, which differentiate into neurons, and it impairs the differentiation of neighbouring cells by activating NOTCH signalling.
'Classically' activated macrophages are monocytes stimulated with IFNγ, alone or in combination with IL-12 and IL-23, which differentiate into M1-polarised cells that induce the differentiation of Th1 type responses.
To define the regulation of Osx transactivation in osteoblast differentiation, we stably transfected Flag HA Osx into the mouse C2Cl2 line, which differentiates into osteoblasts on BMP-2 addition.
In vitro, ES cells aggregate to form embryoid bodies (EBs), which differentiate into multiple cell lineages.
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