The effect, which is demonstrable at the first episode, is also apparent in the early phases of treatment.
NADPH-diaphorase histochemical staining (a selective marker for NOS in neuronal tissues), which was demonstrable in the neuronal cell bodies in the cerebral ganglia, the brain commissure, the main nerve cords and in the innervation of the pharynx, ventral sucker, terminal genitalia and genital parenchyma of the parasite, showed a stronger activity in the treated worms.
Consenting patients completed the Needs Assessment for Advanced Cancer Patients questionnaire, which has demonstrable validity and reliability.
Diastolic ventricular interaction, which is demonstrable in patients with heart failure, is relieved by CRT.
Immunoperoxidase cytochemical methods were employed for the cellular localization of CEA which was demonstrable only on the neoplastic cells.
In 1993, felbamate was marketed as a safe AED, which lacked demonstrable toxic side effects and did not require laboratory monitoring in humans.
In 1999, Dawson et al. reported that PEDF is one of the more potent antiangiogenic factors, which has demonstrable inhibitory activity against ocular neovascularization in vivo (Dawson et al., 1999).
Finally, we will move from experimentation to implementation, and test new strategies to enable the successful dissemination into routine practice [ 42, 43] of those interventions which have demonstrable acceptability and efficacy.
If expression of these genes is modulated during early pregnancy and/or by altered concentrations of P4 in vivo (which have demonstrable effects on the elongation of the conceptus), it is plausible that they are candidate genes likely to influence conceptus elongation.
Examination of brains and spinal cords from animals immunized with the lung-tumour extract or related hepatic metastases which showed demonstrable immunological cross-reactivity with EF in immunized animals, revealed a number of inflammatory changes characterized by dense infiltrates of mononuclear cells sub-ependymally, and perivascular cuffing in the cortex.
