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Biomolecules rapidly adsorb to the nanomaterial, leading to the formation of the protein/biomolecule corona, which critically affects the nanomaterials' (patho biological and technical identities.
Based on ANOVA, we found that the substrate temperature was a key parameter which critically affects the opto-electrical properties of ITO films.
The heat loss from a passive DMFC is usually large and it is therefore critically important to reduce this feature so that the fuel cell can be operated at a sufficiently high temperature, which critically affects the cell performance.
Altogether, the results of cellular targeting studies provide a proof-of-principle for our NtraC model and highlight the particular functional importance of the predicted transition area, which critically affects the rate of protein export.
In addition, our model represents the regulated trafficking of APP by SORLA through the intracellular compartments, which critically affects amyloidogenic and non-amyloidogenic processing pathways [ 20].
However, the levels of PD‐1 in lymphocytes are variable depending on the conditions of the tumor microenvironment, which critically affects cytolytic activity of tumor‐infiltrated lymphocytes.
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Furthermore, using analysis of variance, we found that the substrate temperature was a key parameter which critically affected the opto-electrical properties of ITO films.
Two more aspects of machine learning algorithms which critically affect performances are the selection of specific descriptors that best correlate with the activity under study from the initial pool of descriptors and the definition (and application) of the model's applicability domain, namely, the region in material space in which the model is expected to give accurate predictions.
The authors also discuss the importance of correctly reporting the methods, which critically affect the reliability of the results and therefore our ability to translate fundamental research into clinical practice.
To further clarify GalNAc-T3's function in RCC, we examined expression patterns of two cell-adhesion molecules, β-catenin and E-cadherin, which critically affect cell morphology and carcinogenesis (Yuan et al, 2007; Park et al, 2010).
Moreover, increased levels of reactive oxygen species (ROS) upregulate extracellular signal regulated kinase (ERK) and v-akt murine thymoma viral oncogene homolog kinase (AKT) dependent pathways and inhibit the activity of protein phosphatase 2 (PP2all all of which critically affect photoreceptor survival [ 24, 25].
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