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In addition, all five participating Latin American countries are interested in getting NCI's help to develop molecular profiles of breast cancer in their patients, which could elucidate how breast cancer varies from population to population, and how best to treat it.
These data also highlight the importance of longitudinal studies, which could elucidate the direction and rate of viral migration between these tissues not only during lactation but also in response to inflammatory stimuli [65].
Furthermore, as seizure-induced pathology seems to be age-specific, there could also be age-specific differences in the pathways altered by seizures, which could elucidate in more detail the postulated differences in epileptogenesis between the immature and mature brain.
An advantage to the discovery approach is that it permits detection of novel compounds, which could elucidate a link between genotype and phenotype, thereby providing disease biomarkers.
These results suggest SATB1 as a potential candidate for functional studies, which could elucidate the possible direct involvement of miR-21-5p in response to nCRT in rectal cancer patients.
Also, Liu and his colleagues reported that markedly elevated protein expression of IL-13 was detected in patients with HCV-associated cirrhosis which could elucidate the elevated P-selectins in patients with HCV [ 54].
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Hemophagocytic macrophages may have an anti-inflammatory effect, provide S. Typhimurium a survival niche, and contribute to development of cytopenias, all of which could help elucidate mechanisms of sHLH disease pathogenesis in this natural infectious disease model.
As demonstrated in this study, CypA upregulated the activity of MMP9 in NSCLC cells, which could help elucidate the mechanism of CypA effect on lung cancer metastasis.
We further provide a first characterization of the selective patterns shaping the Brassicaceae plastomes, which could help elucidate the driving forces underlying adaptation and evolution in this important plant family.
Our data indicate clear functional diversity between the inheritance and reprogramming of the ASHM genes in the F1 hybrid, which could help elucidate the regulatory mechanisms of the two types of allelic histone modifications for gene expression profiles.
Then, in a regional-level network connectivity analysis, we compared the degree and centrality of the prior identified abnormal regions (reflecting the connections and roles of a region, respectively, see Section 2), which could help elucidate whether volumetric changes in GM (i.e., GM reduction) were a consequence of the lack of connecting fiber bundles.
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