We detected eSWRs in different locations in the open-field arena, which could be approached from many different directions (Fig. 3C).
However, further studies would be necessary to identify genes that are mutated during IR and to eventually find the mechanism underlying the sensitivity of iPSCs to DNA damage, which could be approached, for example, by comparing the DNA repair capability of more cell types including iPSCs, ESCs and other somatic cells.
Jordan and Minardi are facing the prospect of working on austerity budgets in 2003, each needing to find around £13m merely to lease Cosworth V10 engines for their cars, which could be approaching one third of their overall budgets for the year.
Based on our discussions with study coordinators, we learned that some of the difference in approach rates was due to variations in the interpretation of provincial data protection laws, and by site-specific limitations imposed by hospitals on the conditions under which patients could be approached.
There were two methods of identifying relevant consultations within the different practices: either the researchers attended a practice for a specified chronic disease clinic and recruited waiting patients; or the GP or PN identified patients on their appointment list with asthma, diabetes, CHD or COPD and indicated to reception staff which patients could be approached by the researcher.
However, if a septic patient did not receive APC, then they could become a standard care patient if they survived until day 28, at which time they could be approached for inclusion in the study.
While the more immediate applications for hPSCs are likely to be drug screening and disease modelling, which require fewer cells and could be approached with conventional 2D culture systems; clinical applications demand higher cell numbers and more stringently defined culture conditions for reasons of safety.
"There was this real whiff around conference which suggested we could be approaching freefall as a party," he said.
He added that he thought the Dow, which was then around 9,500, could be approaching a record high "in another 12 or 18 months".
When a researcher believes they may have a specific technology which could be commercialised, they approach the RCT.
In order to evaluate the overall impact on development, a well‐specified growth model has to be employed which could be a promising approach for future research.
