Only few mutants identified in this screen were also attenuated in the mouse infection model, indicating that L. monocytogenes uses a huge number of partially redundant pathways and nutrient acquisition strategies, all of which contribute to its highly physiological flexibility within in vivo compartments.
Only DPS showed obvious desired intracellular deshielding and endosomal escape, which contributed to highly efficient gene delivery.
The high-performance of the NiCo2O4 materials is attributed to their large surface area and highly porous structure which contribute to rich surface electroactive sites and easy ions transport pathways for facile electrochemical reactions.
Many bromodomain-containing proteins have additional regulatory and protein protein interaction domains, which contribute in a combinatorial manner to highly specialized functions as transcriptional regulators, chromatin remodelers, splicing factors, scaffolding proteins and signal transducers.
The arrested GADD45 encodes three highly conserved nuclear proteins, which contribute to cellular homeostasis by responding to stress.
This is a very dynamic process orchestrated by proliferation and differentiation of NPCs, which contribute to the development and maturation of a highly complex neural network.
Subsequent studies have shown that Rho GTPases are involved in highly diverse cellular and biological functions, many of which contribute to tumorigenesis.
MicroRNAs (miRNAs) are a highly abundant class of endogenous non-coding RNAs, which contribute to cancer initiation and progression, and are differentially expressed between normal and cancer tissues.
Sea ice serves as habitat for a unique, highly specialized community of bacteria, algae, protozoans, and metazoans, which contribute to the biogeochemical cycles of polar seas [262].
By varying the crystallite size (40 280Å) of highly dispersed Pt electrocatalysts, the relative concentrations of edges, vertices and crystallite faces which contribute to the surface morphology are changed.
