Sentence examples for which considerably limits from inspiring English sources
Another problem which considerably limits the usage of anticancer drugs is non-specific toxicity.
However, homologous ncRNAs typically have poor sequence conservation which considerably limits the applicability of conserved region detection towards discovery of species specific ncRNAs [5], [21].
These pathogenic processes eventually lead to restenosis, which considerably limits the long-term efficacy of these interventions.
Therefore, many genomes are deposited in GenBank or EMBL/ENA without annotation or with a minimalist and often wrong annotation, which considerably limits their usefulness to researchers.
22 23 Major drawbacks of these previous studies were small sample size and lack of adjustment for confounding variables, which considerably limits the validity of their conclusion.
However, existing parametric algorithms suffer two notorious deficiencies, which considerably limit its further applications: first, typical subroutines for the single-objective subproblem in general cannot capture nonextreme Pareto-optimal paths; second, parametric algorithms for biobjective problems cannot be directly extended to solving multiobjective problems.
WGBS has high resolution, but it is costly, time consuming, involves complex data, and lacks comprehensive analytical tools, which considerably limit its popularity and applicability [ 26].
But its intrinsic structure of phospholipid resulted in the untunable micellar structure with D > 100 nm, which considerably limited the intratumor accumulation.
An osteotomy procedure was conducted nine months after DBS surgery with subsequent complications (necrosis of the head of the femur and chondrolysis), which considerably limited his mobility and quality of life.
The latter may introduce new constants to the program (known as value invention), which can lead to infinite answer sets and non-termination; to prevent this, syntactic safety conditions on programs are common which considerably limit expressiveness (in particular, recursion).
This dispiriting news spread along Broadway, and helped to establish Porter's reputation for elusiveness — a vivid one, only recently dimmed by the war in Europe, which now considerably limits his wanderings.
