Exact(1)
sul1 encodes an alternative form of dihydrofolate synthetase, which cannot be inhibited by the drug [ 22].
Similar(59)
Second, we tested whether impaired inhibitory control of GSK3 was sufficient to alter social behaviors similarly to Fmr1 knockout mice by using GSK3 knockin mice, in which GSK3 cannot be inhibited by serine-phosphorylation.
Hence, GSK3αKI mice, in which GSK3α cannot be inhibited throughout life, may reach a floor effect where their synapses cannot be any further depressed.
Silica cannot be inhibited by conventional phosphonate mineral scale inhibitors.
Moreover, MBLs cannot be inhibited by currently approved β-lactamase inhibitors [ 12].
Expression of a ZAK mutant that cannot be inhibited by vemurafenib blocks this effect.
Regarding their pharmacological mechanism of action, ACE inhibitors have one advantage over ARBs, which cannot be neglected: by inhibiting the converting enzyme, they not only reduce the level of A-II, but also inhibit the degradation of bradykinin, hence enhancing the beneficial cardiovascular effects thereof.
One frequently used evidence is that methylated miR genes could be reactivated by inhibitors of DNA methyltransferase (5-aza-cytosine or 5-aza-deoxycytosine) because these cytosine analogues, which cannot be methylated in DNA, inhibit maintenance methylation through direct replacement of methylation targets (cytosine residues).
These differences may indicate that γ-tocopherol prevents development of prostate cancer, which cannot be investigated in this model, rather than inhibits growth of prostate tumors.
NF-κB signaling was inhibited by transient overexpression of a non-degradable IκBα mutant containing alanine residues in positions 32 and 36 instead of serine residues, which cannot be phosphorylated and degraded [ 34] and thus remains bound to and inhibits NF-κB.
A decrease in the ATP/ADP ratio induces both an accumulation of pyruvate, which cannot be utilized by way of phosphofructokinase stimulation, and a decrease in pyruvate utilization by inhibiting pyruvate carboxylase, which converts pyruvate into oxaloacetate.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com