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While there are many non-model organisms whose genomes have not yet been fully sequenced, the decreasing costs of sequencing have prompted qualitative changes in research strategies, including those relating to the development of molecular markers (which are indispensible for breeding studies) and diagnostics in the agricultural and medical sciences.
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It is a path to liberation that is held to involve distinct, esoteric methods, but without diverging from the philosophical view of emptiness, which is indispensible.
For example, BAF is normalized in CLImAT for elimination of LOR bias, which is indispensible for further statistical modeling analysis of WGS data.
For example, Nedd8, a protein which is indispensible for the activity of Cul1, has been found to co-localise with inclusion bodies in brain sections from various neurodegenerative disease patients.
Through screening all 18 known HDACs, we demonstrated that SIRT1- and SIRT5-mediate deacetylaiton of PML at K487 which is indispensible for H2O2-induced accumulation of nuclear PML and NBs and cell death in HeLa cells [ 116].
The most important component they lack is the three dimensional structure for each transcription factor, because the visualization of the transcription factor, especially binding sites, can help further understanding the mechanism and functions of transcription factors, which is indispensible to structural genomics [ 29, 30].
Meiotic crossovers (COs) are required for the establishment of cohesin-mediated inter-homolog interactions, which are in most organisms indispensible for the bipolar orientation and segregation of recombined chromosomes of maternal and paternal origin [10,11].
However, de la Cova et al. further demonstrate that in a heterogeneous population of cells where dMyc is selectively activated, Dmp53 is required for the increased glycolytic flux in the Myc-overexpressing cells, which is an indispensible step for the Myc-expressing cells to become the "winner cells".
Knowledge of which genes are indispensible is needed for the construction of minimal organisms, which are suggested as platforms for novel bacteria with beneficial characteristics [ 2].
When reviewing your homeowners policy, Macknin says to make sure it includes Loss of Use coverage (also known as Additional Living Expenses coverage), which will be indispensible if you have to relocate for any period of time while your house is being rebuilt or repaired.
As functional data accumulates, it is now possible to identify which individual genes and biological functions are indispensible for the progression of specific processes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com