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We then censor the viral load data at detection limit 25, producing totally 23percentt of below detection data which are imputed at 25 as observed in a real experiment.
However, the algorithm of the domain scores of the SF-36 allows a certain amount of missing scores, which are imputed with the mean value of the completed items of that domain [ 5].
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However, as this was just an exploratory analysis, with many untyped data which were imputed conditioning on HLA loci, these last results need to be confirmed both on our population and replicated in others.
The data set contained less than 1% missing genotypes, which were imputed using the rfImpute function.
This resulted in 64 four-digit HLA alleles all of which were imputed with HLA*IMP 02.
In addition, CVD risk was calculated using cholesterol readings, which were imputed in 15 270 patients.
On average, there were 4.78 missing genotypes for cows and 2.38 for bulls, which were imputed using FImpute [ 22].
Figure 1 demonstrates how PMM and LRD may guard against these problems in 150 simulated observations, of which 50 are missing x, which is imputed once.
Additionally, there was no information on the potential informativeness of missing values which were imputed under the assumption of noninformative missingness.
An exception was made for missing values due to death, which were imputed with the worst case rank at each follow-up.
Figure 2 shows all variables with a P-value <0.20 in the univariate analyses, which were imputed in the multivariable regression analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com