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MULTICOM-RANK and MULTICOM-CMFR are two other predictors which also implemented the first four steps of our pipeline.
We have shown this before in simulations which also implemented auxin-regulated cell divisions, cell expansion and root growth, using a modified Cellular Potts Model [see [ 53]].
FHI 360, the sponsor institution, collaborated on this study with Impact Research and Development Organization (Impact RDO), which also implemented the FEM-PrEP clinical trial with which our study was associated at the Bondo, Kenya site.
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Alternative tools for graph visualization also used in the scientific community include Ondex [4] and yEd [5], which also implement several graph layout algorithms.
This procedure has been implemented in the SCOREASSOC program, which also implements a weighted burden test to detect dominantly acting effects.
It is pertinent to note also that although initially plans were to cover two additional districts namely Kigoma Urban and Geita which also implement CJF under the support of GFATM (not UNICEF) this was not done after the consultants became aware that these districts were still at preparatory stage of CJF program.
An implementation of the RECAP algorithm (Lewell et al., 1998) to fragment small molecules can be found in a commercial program (fragmenter, www.chemaxon.com), and is available in the RDKit library (http://www.rdkit.org), which also implements the BRICS fragmentation algorithm (Degen et al., 2008).
All data (15,476 genes) was classified using those methods (see results in Additional File 1) and we computed the sensitivity of classifying known Wnt/β-catenin pathway target genes, as shown in column 'Prior' in Table 4. KNN was performed using directly 'knn.cv' routine (which also implements a leave-one-out test) over all data and it did not recover the known Wnt/β-catenin pathway target genes.
The fingerprint definition from Gobbi's work [26], which is also implemented in RDKit, was used in this study.
The processing time required for the proposed method is compared with AINDANE and MSR methods, which are also implemented in C++.
The lessons derived are contrasted to the other two jurisdictions which have also implemented quotas on their vehicle registrations namely, Shanghai and Beijing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com