Sentence examples for which activates as from inspiring English sources

Glutamine, fructose-6-phosphate amidotransferase, is the rate-limiting step of the hexosamine biosynthesis pathway, which activates as an alternative pathway to glycolysis for the utilization of hyperglycemia-induced overproduction of fructose-6-phosphate, resulting in excess of N-acetylglucosamine and irregular alteration of gene expression of plasminogen activator inhibitor-1 and TGF- β.

Saad et al. (2016) concluded that maternal diabetes increase the oxidative stress in placenta, which activates apoptosis, as well as disorganized the endothelial and vascular placental functions.

Chitosan is capable of promoting platelet adhesion by initializing a cascade of intracellular signaling which activates glycoproteins IIb/IIa as well as thromboxane A2/ADP, increasing platelet spreading and strengthening the stability of adhesion [ 97].

To explore the role of PDK1 in the regulation of PKD activity, wild-type or PDK1−/− pre-T cells were isolated and left unstimulated, stimulated with a crosslinking α-CD3 antibody (to activate preTCR signalling) or were stimulated with the phorbol ester PdBu (a diacylglycerol mimetic which activates classical/novel PKCs), as indicated.

We examined the breast cancer cell lines for Ret-mediated motility in response to GDNF, which activates Ret, as shown by an increase in its phospho-tyrosine content (pY) [ Fig 2A and (Boulay et al, 2008)].

The above result is consistent with the function of CBFs, which activates cold responsive genes as well as other abiotic stress responsive genes [12].

When we stimulated Dupuytren's fibroblasts with TPA, which activates ERK1/2/MAP kinase pathways (as well as other pathways), we found elevated α-SMA expression and collagen contraction (Additional file 4, Supplementary Figure 4).

Or by using Sellaround's "crowdsaving" widget type, which activates a deal for everyone as soon as the widget was shared by enough people.

FAK can promote cell cycle progression through activation of ERK and induction of the transcription factor Kruppel-like factor 8 (KLF8), which activates transcription of cyclin D1, as well as through inhibition of p27(Kip1) expression in glioblastoma cells [13] [15], [17].

In the scenario of option (3), negative feedback regulation of activated ERK1/2 on B-Raf [ 47] could therefore be overridden by positive feedback via Cdc42 and p21 activated kinase, which activates C-Raf [ 36], as long as the complex is bound to actin.

It has been also suggested that activated IRE1α can recruit tumor-necrosis factor receptor associated factor 2 (TRAF2), which activates procaspase-4 as a mitochondria-independent apoptotic response.