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In summary, IGF/INS ligand binding leads to the activation of IGF1R, INSR and IRR, which activate a complex signalling network across the two major signalling pathways PI3K AKT and RAS RAF MAPK.
Cellular activity and behavior are mediated by internal and external cues, which activate a number of small GTP-binding proteins of the Rho family (Hall 2005) and thus orchestrate actin filament dynamics by coordinative activation of a number of actin-binding proteins (ABPs) (Pantaloni et al. 2001).
Upon arriving at their final destination, they begin to differentiate, in response to signals from the immediate surroundings, which activate a genetic program that causes each to acquire the properties of a specific subtype of neuron.
This is triggered by superantigens, which are powerful toxins produced by the bacteria and which activate a large number of the human immune system's T-cells in the bloodstream.
However, the immune responses of Drosophila can be 'primed' by exposure to certain pathogens, which activate a set of intra- and extra-cellular pathogen recognition molecules under complex control [21], [22].
RNase L is activated in response to viral infection and the presence of virally encoded dsRNA mobilizes the type I interferons (IFN), which activate a family of 2'-5' oligoadenylate synthetases (OAS) [6], [7].
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For example, osmotic stress activates several transcription factors, including NAC proteins, which activate an early response to dehydration1 (ERD1) [ 37].
In particular, elevated levels of ET-1 activate ETA receptor, which activate an integrin-linked kinase- (ILK-) mediated signaling pathway.
Space shift keying (SSK) is a MIMO technique which activates a single transmit-antenna during each time instant and uses the activated antenna index to implicitly convey information [8].
A second drug, xamoterol, which activates a specific subset of norepinephrine receptors, had the same effect.
The notochord forms beneath the neural tube and secretes retinoic acid, which activates a gene called sonic hedgehog in cells at the bottom of the neural tube.
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