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It remains unclear whether this derives from a lack of description concerning outcome measures or insufficient discussion on the need for QOL assessment.
49 The individual parishes do show some differences in average ages as well, and it is difficult to tell whether this derives from changes in apprenticing practices, or from local opportunities and aims.
Thus, while abundance of PR provides prognostic information beyond ERα positivity, the important question is whether this derives from the intrinsic biological activity of PR, or is purely due to PR acting as a marker of the extent of tumour cell ERα activity or responsiveness.
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It did not focus on the wider context – the slow and lacklustre response of the US government and military to the disaster, and whether this derived from the poverty of the region and the colour of its inhabitants – except for occasional outbursts of rage from the mayor.
I'm wondering if there are other examples of this approach and whether this derived level of analysis is appropriate.
Recently, a shorter form of BAG3 (40 kDa) has been characterized by immunoprecipitation from neural synaptosomes homogenates and successive mass spectrometry, again it is yet unknown whether this form derives from the alternative splicing or proteolytic processing.
To test whether this pattern derives from interaction effects at the level of gene activity, we here performed metabolite and whole transcriptome profiling on third-instar larvae from 20 of the highly inbred lines chosen to represent the range of phenotypic diversity in our larger panel (Reed et al. 2010).
We have not determined whether this signature derives entirely from tumour cells, given that we did not enrich for tumour cells in our experiments; however, the fact that all of the primary tumours showed at least 70% tumour cells by histology would support the idea that the tumour likely contributes substantially to the signature we noted.
These results indicate that, as in humans, loss of TPP1 activity in Dictyostelium results in the accumulation of autofluorescent bodies within cells, although whether this autofluorescence derives from the same molecules in Dictyostelium as in individuals with NCL is currently unclear.
Whether this conclusion derived from in vitro systems extends to the in vivo situations remains to be shown.
We initially considered whether this result derived from an artificial increase in the measure of bone density by DEXA due to the presence of lead in bone.
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