The apparent lack of the GP-motif in some fungal tRNase ZLs and all fungal tRNase ZSs that we have examined raises the question of whether this motif is absolutely required for substrate binding.
We have not performed CGH on multiple independently derived cell lines, so we cannot say whether this change is absolutely required for transformation with CCND1, PI3K-H1047R, MYC, TERT, BMI1 and sh-p53, but it seems unlikely.
This is absolutely ridiculous, regardless of whether you're pro-drone or anti-drone -- pro-white paper or anti-white paper.
Critics wondered whether public education absolutely required repeated references to "my historic tax relief plan".
At G7, Cameron was asked whether he had "absolutely closed his mind to allowing ministers a free vote".
When asked whether he was absolutely certain the centre-half would stay, Benítez said: "For me, 100%.
At the G7 summit in Bavaria, Cameron was asked whether he had "absolutely closed his mind to allowing ministers a free vote".
During the flight she came up to me several other times, asking me whether I was absolutely sure I didn't know her family.
"We've all naturally been thinking about whether it's absolutely essential to have a lunch here or there," Mr. Burnham added, "or whether it can be a phone call or a meeting".
"I had no idea whether I was absolutely out of my mind until we ran our first advertisement, and all the diehard train lovers came out of the woodwork," he said.
"You need to take a judgement on whether it's absolutely essential, is it really going to help your baby?
