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The concern was whether sufficiently high levels of anti-Aβ antibody can be safely produced in humans.
Both approaches are of interest in testing whether sufficiently strong effects in a single population could still emerge as signals upon meta-analysis.
There is also concern whether sufficiently selective SPAK/OSR1 kinase inhibitors could be synthesized for the management of a chronic largely asymptomatic condition, without them inhibiting other protein kinases or ATP-binding enzymes and causing intolerable off-target effects.
Although ATN-224 has also been shown to have antiproliferative and/or proapoptotic effects on tumour cells in vitro (Juarez et al, 2006), it is yet unclear whether sufficiently high concentrations of ATN-224 can be achieved and maintained in the tumour environment in vivo to elicit those responses.
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Try to look at the paragraph objectively and decide whether it sufficiently supports and develops your topic sentence, or whether it needs a few more details or additional evidence to back up your claims.
"I look forward to having meaningful consultation with the administration on these matters, and reviewing its proposal to evaluate whether it sufficiently protects Americans' privacy.
"One issue is the deception issue, and whether viewers sufficiently understand that they're watching an advertisement, even if it's an entertaining advertisement," Mr. Weissman said.
The Kadison Kastler problem asks whether two sufficiently close von Neumann algebras are spatially isomorphic.
We recommend investigating whether tartazine-like substances also reach sensitive sites, e.g. pulmonary epithelial cells, in this form (stability testing) and, if so, whether they sufficiently accumulate there, have a similar interaction with the GC receptor and act as allergens.
The report has been challenged by terror experts in France, who have questioned whether it sufficiently represents the various contexts of radicalization.
This analysis provides a straightforward test whether a (sufficiently large) perturbation can "invade" the initially uniform steady state solution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com