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The role of the direct effects of metformin on breast cancer cells, whether mediated via AMPK or otherwise, remains an open question to be explored in future pre-clinical and clinical studies.
This finding confirms that 3′ BE-mediated mRNA targeting is an event separate from mRNA docking (whether mediated by the -box or the U1A 'bypass'bypass
Our results suggest wolves influence cattle behaviour but we did not measure subsequent fitness costs (whether mediated by stress, changes in forage intake, or something else).
However, we have previously used D-isomeric 1mT to successfully inhibit in vitro HIV-induced tryptophan degradation and kynurenine production [32], suggesting that this molecule has a significant effect on tryptophan catabolism, whether mediated by IDO or IDO2.
Disease severity is thought to be a consequence of the raised viral titre and the resulting pathology (whether mediated directly by the virus itself or by immune responses, cellular or otherwise) is therefore correspondingly more severe than that in primary infection.
These effects, whether mediated by junctional communication or extracellular secretion, are significantly modulated by COX-2.
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To investigate whether neurally mediated syncope (NMS) is associated with low iron storage or serum ferritin (SF).
We next tested whether bacterially mediated RNAi could be explained by dsRNA leakage from bacteria.
We further investigated whether fiber mediated receptor masking is a general mechanism in adenovirus infection.
Since CD40 was found to complex with class II, we asked whether CD40 mediated NFκB activation in DCXAb.
Here, we investigated whether adrenomedullin mediated FLS adhesion to extracellular matrix (ECM) proteins.
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CEO of Professional Science Editing for Scientists @ prosciediting.com