We provide a solution that allows relatively quick (∼3.5B reads from 238 sequencing lanes providing 81× average coverage of a 3 GB human genome, processed in 12 hrs) and flexible hypothesis testing that is targeted to a genomic region of interest, whether it comprises a fusion, translocation, SNV or SNP.
Pyromania is regarded as an impulse-control disorder, but controversy continues over whether the condition should be classified under the impulse-control disorders or, indeed, whether it comprises a separate entity at all.
For example, although "Attribution" of NSPS to EMF could be considered as a first indication of suffering from IEI-EMF, it is questionable whether it comprises a sufficient identifying criterion when used alone.
Eric Holder, the head of the US Justice Department, said last October: "As the so-called 'war on drugs' enters its fifth decade, we need to ask whether it, and the approaches that comprise it, have been truly effective… Today, a vicious cycle of poverty, criminality and incarceration traps too many Americans and weakens too many communities.
I wonder, though — first, whether a postmodernist style is itself comprised of modernist elements; second, whether it's right to say that Mailer didn't develop one; and, third, whether Mailer was indeed not inspired by literary modernism.
The latter is dealt with by Directive 2001/18/EC [4] on the deliberate release of GMOs and Regulation 1829/03 [5] on genetically modified food and feed including seed (IT is controversial whether seed is comprised by the Regulation. However, it is common practice) [6].
Throughout the development process, clinicians were consulted for instance to evaluate items on their relevance for evaluating treatment progress and whether items comprised behavior observable to others.
In this study we have tested whether Cl− channels (whether comprising Ano6 or other proteins) can regulate platelet PS exposure.
At the moment it is unknown whether EOA comprises a separate disease entity with specific risk factors and pathogenesis or a more severe stage of hand OA.
