At the same time, the agency also implemented process reviews whereby its requirements become more aligned over time to established regulatory authorities as a result of the gradual adoption of internationally recognized guidance documents, scientific principles and best practices.
Second, that we must take into account how family migration involves a 'double conditionality' whereby integration requirements target both the civic deservingness of the resident sponsor and the civic integration potential of an incoming family member.
For example, human anti-chimeric antibodies are a significant cause of secondary inefficacy of infliximab, whereby mAb requirements increase with time and treatment may eventually become ineffective [ 13].
Because GNMT, which catalyzes the nonessential methylation of glycine to sarcosine, competes for SAM and generates SAH, lower activity during periods of rapid growth may be one mechanism whereby increased requirements for SAM during growth and development are achieved.
The 'Heneberg Compromise' operates whereby the conflicting requirements of tunnel stability and ease of excavation dictate the optimum particle size for usable ground.
Regulatory convergence represents a voluntary process whereby the regulatory requirements across economies become more similar or "aligned" over time as a result of the gradual adoption of internationally recognized technical guidance documents, standards and scientific principles (harmonization) and common or similar practices and procedures.
These safeguards include the "necessity" and "participant-condition" requirements, whereby the research cannot reasonably be performed in a non-vulnerable surrogate population and the participant must have the specific condition being investigated.
Subject condition requirement, whereby the research must involve a condition from which the subject suffers.
It's an open question whether this approach is superior to an import allowance requirement, whereby imports of a small set of specific commodities must carry with them CO2 allowances.
One alternative approach is an import allowance requirement, whereby imports of highly carbon-intensive goods (in terms of their manufacture) must hold allowances for the U.S. cap-and-trade system, mirroring requirements on U.S. sources, if those imports come from countries which have not taken comparable climate policy actions.
