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Our query program identified 5, 28, and 56 metabolites in these samples, respectively (whereby compounds with multiple isomers are counted only once).
The epithelial pathway is a significantly faster route for direct nose-to-brain transfer, whereby compounds pass paracellularly across the olfactory epithelium into the perineural space, which is continuous with the subarachnoid space and in direct contact with the CSF.
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Understanding the precise molecular mechanism whereby ELN compounds modulate the γ-secretase activity would pave the way to develop a potentially safe and effective compound to attenuate β-amyloidosis in AD.
Autophagy is the process whereby cytoplasmic compounds and organelles are sequestered into vacuoles for degradation and recycling [1].
The strategy whereby related compounds are employed both for diagnosis and therapy is generally referred to as 'theranostics' [2,3].
Furthermore, modulation of testosterone production by phthalates in the male fetus could be another potential mechanism whereby the compounds could disrupt sexually dimorphic behaviors.
This review explores the process whereby polar compounds, hexamethylene bisacetamide (HMBA) in particular, induce murine erythroid leukemoid cells (MELC) to express the differentiated erythroid phenotype, including hemoglobin production and cessation of cell division.
Furthermore, Basi and colleagues revealed an intriguing finding regarding the molecular mechanism whereby these compounds confer APP selectivity by employing a chemical biology approach: only in the presence of the recombinant APP substrate were ELN compounds able to displace the active site isostere that directly targets both catalytic aspartates in PS1.
Our results show that this interaction promotes the decomposition of the highly reactive pro-inflammatory oxidant, whereby MPO Compound II (but not Compound I) is formed.
This review will focus on the anti-atherogenic and anti-carcinogenic effects of lycopene, and point out areas for future research to further elucidate mechanisms whereby this compound may reduce cancer and cardiovascular disease risk.
Fluorescence interference will primarily be due to inner-filter effect, whereby the compound absorbs the excitation or emission wavelengths of 1-AMA.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com