A low amount of hydrolysate (corresponding to 2.5 % WIS) is optimal, whereas higher amounts decrease cell mass yield during propagation.
Nalesso et al. demonstrated that low amounts of WNT ligand can activate non-canonical signaling whereas higher amounts activate the β-catenin mediated pathway [ 45].
However, the effect on Notch signaling appears to be dependent on ligand abundance, since low-density Delta-1 enhances proliferation of CD34+ cells, whereas higher amounts induce apoptosis of CD34+ precursors [ 81].
Histological staining also revealed that no free iron was deposited in the liver of control rats (Fig. 3a) whereas high amount iron deposition was found in liver section stained for the free iron depot in CCl4 treated rats (Fig. 3c).
The characterization of the obtained copolymers by GPC and 1H NMR demonstrated that the influence of polymerization temperature in the range of 110 150 °C on the efficient incorporation of branching units was not pronounced, whereas high amount of catalyst was the key point.
At 900 °C, a mixture of oxynitride (TaON) and nitride (Ta3N5) material phases was observed for lower flow rates (i.e., 50-100 min−1n−1 NH3), whereas a higher amount of the Ta3N5 phase was observed at higher flow rates.
There was low content of dissolved oxygen in water samples from site S1 whereas significantly higher amount of oxygen was available in the water at rest of the sampling sites.
1×102 SP cells were able to form tumors whereas significantly higher amount of non-SP cells (1×104 cells) were required to initiate tumor formation (Table 1).
The majority of genes detected in Oryzias latipes and Danio rerio show smaller distances, whereas a higher amount of genes in both pufferfish species seem to have evolved faster (59%).
