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In Zulip's case, its take on messaging was one which sees it focused on conversations over more basic "chats," where topical streams include subject lines and threaded replies.
As luck would have it, I was offered a job as a reporter for The Home Show, an ABC network daytime talk program, a predecessor to programs like The View, where topical subjects became a platform for discussion.
This is different from other countries where (topical) antibiotics are even prescribed by telephone.
Spruance et al. 2000 [ 21] conducted a trial on 29 participants where topical corticosteroid with valacyclovir 2gm was compared with antiviral alone.
26 Where topical therapy fails to provide suitable control, or the lesions are too widely distributed for topical application, phototherapy may prove a useful adjunct.
Oral ivermectin is often used for crusted scabies in immunocompromised patients or during outbreaks where topical treatment is seen as impractical.
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In cases where a topical gel has previously been applied to the vaginal epithelium, virions must move through gel layers before reaching vulnerable tissue.
Thus, although the lesion in the dermis does not heal within 24 h after the CO2 laser treatment, the epidermis has completed the complex epithelization, including the formation of the stratum corneum, where the topical drug could not penetrate through channels.
Extraordinary enhancement of toxicity has been found with addition of commercial synergists to fluvalinate, where a topical LD50 of 0.00964 µg/bee, a 980-fold increase to their reported 9.45 µg/bee without the additive, occurred if 100 µg of piperonyl butoxide was applied 1 hr prior to the pyrethroid [71].
This concept is supported by findings from previous studies where the topical application of NSAID's led to lower plasma levels as compared to systemic administration, whilst still maintaining efficacy [ 8– 10].
Two interviews described cases where medication (topicals and IV fluids) had been given but had not been prescribed on the system and so an eP administration record could not be made.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com