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The therapeutic potential of the Apaf-1 inhibitor was confirmed in vivo, where it prevented mesothelial cell loss induced by either TNFα/IFNγ or by bacterial peritonitis.
We have already demonstrated an antioxidant function of TAT-administered α-syn in rat PC12 cells, where it prevented H2O2 oxidative damage by raising the HSP70 protein level [36].
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P-glycoprotein (P-gp) is an ATP-dependent 170- to 180-kDa transmembrane glycoprotein present at the luminal side of the BBB where it prevents its substrates from entering the brain.
This saturation reaches a threshold where it prevents further brain processing, and so, you then experience 'burnout'burnout
The first time it happens, it's really, really freaky because there's no other point in the game where it prevents you from moving like that".
Labour's shadow home office minister, Diana Johnson, has kept her options open in recent weeks, saying: "We support a minimum unit price where it prevents too low supermarket prices whilst protecting responsible pubs.
This species presently covers 20-30% of the rangelands in the lower Tana, where it prevents grass growth under canopy (as shown in this study).
The X-linked inhibitor of apoptosis protein (XIAP) is overexpressed in several malignant cells where it prevents apoptosis by binding to, and blocking, the activation of caspase-3, -7, and -9.
IpaD [Ipa (invasion plasmid antigen)] is the first protein to localize to the T3SA needle tip, where it prevents premature effector secretion and serves as an environmental sensor for triggering recruitment of the translocator protein IpaB to the needle tip.
In a similar fashion, RACK1 associates with the NMDA receptor where it prevents phosphorylation until the interaction is disrupted by stimulation [23].
Surfactant is present at the interface with air, where it prevents the alveolar collapse by lowering surface tension.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com