Sentence examples for where efficacious from inspiring English sources

A new area of vaccine research will also be touched upon, where efficacious responses are elicited by inhibiting the natural negative regulators of immune responses, such as Treg cell products and SOCS proteins.

In addition, where efficacious, IPT reduced health system costs and showed significant savings to households from malaria episodes averted.

Where efficacious, based only on intervention costs, IPTi was shown to be cost effective in all the sites and highly cost-effective in all but one of the sites, ranging from USD 2.90 (Ifakara, Tanzania with SP) to USD 39.63 (Korogwe, Tanzania with MQ) per DALY averted.

10 13 A significant decrease in VTE incidents has been reported where efficacious and cost-effective treatments (ie, pharmacological and mechanical prophylaxis) were used for medical as well as surgical patients.

This is particularly problematic in the context of poorly resourced healthcare settings where even efficacious interventions fail to translate into improvements in health.

Recent regulatory approval of a number of cancer therapies on the basis of a PFS advantage underscores the increasing importance and validity of PFS as an end point in phase III clinical trials of oncologic agents where multiple efficacious lines of therapy are accepted clinical standards or where there is unmet clinical need.

An in vivo selectivity of >65 for ELN475516 based on either dose or terminal plasma levels of compound is estimated, where minimal efficacious dose is defined as ≥25% Aβ reduction in the brain at study termination (that is, three hours post last dose), and the minimum toxic dose is defined as the dose producing a statistically significant elevation of Math1 mRNA levels.

Indeed, a role for enzalutamide in all patients with metastatic CRPC is hinted at by the data from the Phase I/II studies, where enzalutamide appeared efficacious (and potentially even more efficacious) in chemotherapy-naïve patients.

De generatione et corruptione 1.5, 322a11-13, where the causally efficacious entity in the growth of flesh is located in the growing entity itself, and it produces flesh in actuality out of the nutriment, which is flesh in potentiality).

In nearly all of the studies where IPT was efficacious, it was highly cost-effective.

In an effort to improve survival in luminal-B breast cancer, there has been a recent focus on particular molecular pathways where development of efficacious therapeutic agents may alter the natural history of the disease.