Use of these techniques has to be authorised internally by an authorising officer or a designated person, and can only be used where it is considered necessary and proportionate.
Results reveal that disciplinary knowledge and medical editing experience did not significantly impact editing strategies, but did impact the number of points where consultation was considered necessary, as well as revisions affecting definite articles.
This heightened focus on engineering design is evident in the Framework of the National Research Council (2012) where it is considered necessary for a literate society who can effectively tackle issues of local, national, and global importance.
Fixation for a short period of time is allowed in cases where this is considered necessary to ensure piglet welfare, or in case of illness.
Clarifying and confirming questions were asked where more information was considered necessary, or to avoid interviewer assumption.
There are many situations where it may be considered necessary to include evidence from observational studies such as non-randomised comparative and case series studies [ 1].
In case of GERD symptoms without esophagitis on endoscopy or where endoscopy is not considered necessary (esophagitis prevalence in the general population not exceeding 2%) [ 1], treatment aims at rapid relief of symptoms (heartburn, acid regurgitation).
Therefore, consistent with the current model of SOCE where Stim1 Orai1 clustering is considered necessary and sufficient for the physiological activation of SOCE, CRACR2A regulates the formation of Stim1 Orai1 clusters (Srikanth et al., 2010; Lewis, 2011; Soboloff et al., 2012).
It is a single-center study with a relatively short median follow-up (8.3 months) and with a limited number of cases having available histological specimens (due to the advanced stage of many subjects where biopsies were not considered necessary for HCC diagnosis).
