Sentence examples for when the variant is from inspiring English sources

As in the case of the gene expression profiles considered above, the mean accessibility levels were already high at the UI stage when the variant is incorporated, and the high accessibility levels were maintained after differentiation (Supplementary Fig. 19).

The edge effects are much easier to isolate and study when the variant is present in only one amplicon.

Less than 93% of the simulated variants were recoverable when the variant is 2 bp away from the end of the read.

Based on these results, only 66% of the simulated variants were recoverable when the variant is only 1 bp away from the end of the read.

However, leaky splicing can be assessed by comparing the frequency of the causative allele to the normal allele in the same cell line when the variant is present within the sequenced reads.

However when the variant is co-inherited with a pathogenic mutation it worsen the disease phenotype which suggest a possible molecular effect on protein features as suggested by the Grantham Matrix Score (Table  1).

Nor were they more likely to be depressed when the variant was combined with childhood maltreatment.

These 43 variants were classified as pathogenic (44%), likely pathogenic (17%), or a variant of unknown significance when the variant was in a gene directly related to the patient's cancer (39%) (Figure 2b, Supplementary Table S9 online).

Imbalances that were not associated with well-characterized human syndromes were defined as "likely benign" when the variant was well documented to occur in the normal population on the basis of public databases (http://projects.tcag.ca/variation) or internal lab experience which includes analysis of about 16,000 individuals.

Whereas both the variant and wild type protein possess similar selective cytotoxicity against cancer cells following transfection, only the variant is cytotoxic when added externally.

These effects are more significant when the Ser variant is overexpressed: the pAKT increase after overexpression of the Cys variant is nonsignificant.