Her later books rarely rise to the level of "Death and Life," except when they recapitulate it.
Indeed in one such study in the budding yeast where DNA combing combined with DNA fiber fluorography was used to deduce the replication profile in Chr VI it was found that all yeast VI chromosomes showed different replication profiles when analyzed as single molecules, while recapitulating microarray data when averaged [29].
Moreover, this process was more faithfully recapitulated when implementing the EB method than when using the attachment culture technique, suggesting a significant influence of the precise method on the ES cell differentiation process.
However, the reduced protein secretion observed in the Δ trs85 and Δ rho- 3 mutants when conidia were directly inoculated into Avicel (Fig. 1) was not recapitulated when mycelia of these mutants grown on VMM was switched to Avicel, CMC or Miscanthus, although the Δ trs85 mutant consistently trended below that of wild type with regard to protein secretion and enzyme activity levels.
The tendencies to revise and even recapitulate, when copying manuscripts, are readily understood.
These results were recapitulated when lactacystin was used as a proteasomal inhibitor.
These in vivo findings were entirely recapitulated when ESCs were purified from patients with and without a history of RPL and decidualized in culture.
However, further studies will be required to definitively determine if these VHL-associated pancreatic manifestations can be recapitulated when Vhl is specifically deleted in progenitor cells of ductal, exocrine or endocrine lineage.
Compared to wild-type littermates, hepatocytes with the loss of Tsc1 have reduced SREBP1c and GK expression while ATGL and PEPCK were elevated, and these differences were recapitulated when fed a high-fat diet.
Interestingly, as shown in the present study, the embryonic phenotype is recapitulated when Dicer is deleted post-natally, which demonstrates that miRNAs are not only essential for SMC differentiation during the development of the vasculature but are also required in order to maintain the differentiated state of the SMC postnatally.
