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When one treatment failed, another became available.
Under the flexible design proposed elsewhere, we discuss for cluster randomization trials sample size calculation with a given desired probability of correct selection to choose the best treatment when one treatment is better than all the others.
ICERs give the additional cost per unit of effectiveness gained when one treatment alternative is compared to another [ 29, 30].
The LHS offers a potential means of using highly advanced electronic triggers to help with advising when one treatment or diagnosis is favoured.
Although there is no definitive evidence indicating when one treatment modality is superior to the other, this section will discuss the advantages of both options and attempt to clarify this challenging dilemma.
It is therefore clear that, although prognostic models may be useful for research purposes and when one treatment option is available (such as the standard platinum-taxane combination), predictive models have a much greater part to play in stratified medicine where the aim is to identify the most appropriate treatment on a patient-by-patient basis.
Similar(54)
The overall drug exposure difference is more pronounced when one considers treatment regimen; on the average TPV/r patients with CD4+ counts above 200 remained in the study 8 month longer than their CPI/r treated counterparts (data not shown).
Combinations of suggested preventive treatments are recommended especially when one preventive treatment decreased the attack frequency but did not controlled the situation satisfactorily, upon the physician's decision.
Preventive medication should be preferably used as monotherapy but a combination is suggested when one preventive treatment is not completely effective [7].
It is not uncommon for randomized trials to report relative risk reductions larger than 50% when comparing one treatment with another [ 11- 13].
The first difficulty in assessing counterfactual causal effects is to choose the reference condition when comparing one treatment level t with another treatment level c, that is, the substantive meaning of "treatment c".
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