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The four putative effector proteins were fused with ß-lactamase (Bla), which can cleave CCF4-AM to change its emission spectrum from green to blue when it is translocated into the cytoplasm.
p21 inhibits apoptosis only when it is translocated from nucleus to mitochondrial membrane.
β-catenin can function as an oncogene when it is translocated to the nucleus, binds to Tcf/Lef family members and transactivates its target genes [ 39].
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This block of genes would have accompanied the integron when it was translocated from one V. cholerae chromosome to the other.
Once Fe is absorbed through roots, it is translocated to the aerial parts of the plant.
Ultimately, the definitive feature of an effector is that it is translocated into host cells.
Subsequently, it was translocated into the germinal vesicle of vitellogenic oocytes.
In unstimulated cells, NFκB is sequestered in the cytoplasm of cells and activated when it is phosphorylated and translocated to the nucleus.
This variation in the timing of V-host compartment interactions most likely stems from a difference in the kinetics of V trafficking that occurs when V is translocated during a natural infection compared to that by PA-mediated uptake.
However, simulations of unfolding induced by the AFM and when a protein is translocated through a pore suggest that each process occurs by distinct pathways.
When cytohesin-1 is translocated from the membrane to the cytosol, LFA-1 is inactivated on DCs [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com