One of the kinases, a 42-kilodalton serine(threonine) kinase (PK42), was found to possess two- to fourfold-higher in vitro activity when isolated from serum-stimulated cells than when isolated from serum-starved cells.
However, their limited number, especially when isolated from umbilical cord, prevents broader application of HSC-based therapies.
When isolated from river inputs, the marshes subside and deteriorate to open water, resulting in ecological and economic losses.
When isolated from mouse colon, cKit cells promoted formation of organoids from Lgr5 stem cells, which expressed Kitl/stem cell factor, the ligand for cKit.
Though activated NK cells potently kill many tumors in vitro, they display relatively little or no activity when isolated from normal naïve animals or patients.
In this study, we characterise the mitochondrial activity of neutrophils and find that when isolated from different tissue niches, neutrophils possess distinctly different metabolic phenotypes.
Neurons within the lower (lumbosacral) spinal cord can also adapt when isolated from the brain by means of a thoracic transection.
It is generally believed that CPG is capable of producing rhythmic movements, such as swimming, walking, and flying, even when isolated from brain and sensory inputs.
We investigated the efficiency of autologous bone grafting in a well-vascularised muscle environment, and additionally when isolated from the muscle and connected only to the bony environment.
In the writing of Language, Bloomfield claimed that linguistic phenomena could properly and successfully be studied when isolated from their nonlinguistic environment.
These results provide the first direct evidence that hippocampal neurons are capable of producing synchronized slow-wave activity when isolated from pulsed rhythmic inputs of the medial septum and other brain regions.
