The kidneys in such edematous states need not themselves be diseased; for example, normal kidneys, in a patient with heart failure, may retain sodium when handicapped in their function by poor circulation and by abnormal amounts of sodium-retaining hormones, such as aldosterone.
When not handicapped by regulations designed to subsidize the private sector, the public sector often provides services faster, cheaper and more effectively.
Chepstow was active as a port until the 19th century, when larger vessels were handicapped by the shallow draft and narrowness of the channel.
Coleman is now suffering the brickbats that Pearce suffered in his early days at Fulham when his performances were handicapped by injury.
Pakistan has admittedly been handicapped by periods, like the present, when it cannot play at home because of security concerns.
He said he decided to start the process this early because he was handicapped by a late start in 1998, when he was only able to raise about $50,000, compared to Mr. Forbes's $800,000.
But his prospects of being in pink when the Giro finishes in Verona in three weeks are likely to be handicapped by the fact that he wants to save his best for the Tour de France in July.
While we sympathize with the calls for fair burden-sharing when it comes to illegals, Europe faces a bigger immigration problem if Frontex is handicapped by political squabbles.
The English team's offense has been handicapped by injuries to striker Wayne Rooney, and the team lost its captain, Rio Ferdinand, when he damaged knee ligaments in practice last week.
Inoki rebuffed Ali by pointing out he had been unfairly "handicapped by the rules that said no tackling, no karate chops, no punching when on the mat".
