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When formulated in the nanoparticle formulation liposome-protamine-RNA (LPR), modified mRNA showed increased nuclease tolerance and was more effectively taken up by tumor cells after systemic administration.
The task seems to have been set forth of determining what known fixed point results from the usual metric setting remain valid - after adequate modifications that should as much as possible reflect the nature of the concept of partial metric - when formulated in the partial metric setting.
Although compressive sensing (CS) has been employed to estimate a sparse set of plane waves when formulated in the spherical harmonics domain, its performance at the low frequency is still not fully discussed, particularly if the plane waves are densely discretized, the columns of the sensing matrix will become highly correlated.
These considerations are particularly intriguing when formulated in the context of the endosymbiotic origin of the plastid that is derived from the capture of a cyanobacterium ca. 1.5 billion of years ago [ 6, 7].
Similar(56)
In accordance with CD4+ T cell responses, Ag85B-ESAT-6 did not confer any protective efficacy when formulated in Alum, as the number of CFU in spleen and lungs was as high as in control mice regardless of age at immunization (Figure 6A,B).
Our results demonstrate that the novel compound P-I is a strong agent against breast cancer, especially when formulated in liposomes, and establish the critical role of the Trx system in mediating this effect through downstream redox signaling.
When formulated in operator or matrix form, the Magnus expansion furnishes an elegant setting to build up approximate exponential representations of the solution of the system.
However, when formulated in 10 % EtOH/PBS (pH 7.5), the product is unstable, with the initial radiochemical purity (RCP) of 95 98 %, decreasing to 40%% after 20 minutes and 2 % after 90 minutes.
Thus, when formulated in a dry tablet dosage form, the NMs in this work show more than a 10-fold increase in preocular retention in vivo compared to conventional spherical microparticles.
The missions of the energy cooperatives have many similarities when formulated in abstract statutory terms.
And second, the algorithm implementation is significantly simplified when formulated in a reduced five-dimensional Euclidean space.
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