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As this observation reminds us, a key to navigating so many strategic considerations relating to hepatitis prevention and treatment for PWID is knowing when more evidence is needed and when it is time to act on the limited available evidence in the interest of trying to save as many lives as possible.
More generally, investigators who are excessively confident in their own judgments and abilities are less likely to seek additional evidence, even when such evidence is needed, or to enlist the help of others from whose expertise they might benefit.
It ensures that evidence is carefully and critically examined and stimulates additional research when more evidence is needed.
When additional documentation or evidence is needed, include that information beneath your summarizing paragraph.
In the setting of a non-significant result, trial sequential analysis helps decide whether "more evidence is needed" (when the futility boundary is not crossed) or rule out a given effect size (if the futility boundary is crossed), thus reducing this uncertainty.
Functional/orthodontic pacifiers reduce the prevalence of open bite when compared to the conventional ones, but evidence is needed concerning the effects on posterior crossbite.
While observational studies suggest that telemedicine may have clinical and economic benefits when compared with consultation by telephone, formal evidence is needed.
What more evidence is needed?
What more evidence is needed for change?
How much more evidence is needed?
More evidence is needed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com