Your English writing platform
Discover LudwigExact(4)
Membrane ER-α either is increased or stays in the membrane when efflux occurs.
We proposed that ATP5G1 overexpression would sensitize MPT induction; therefore, the threshold for mPTP opening should be reached faster when efflux systems are saturated.
These detailed observations from the multiple simulations can explain why the experimentally measured substrate uptake is not necessarily impaired when efflux is reduced by mutation.
Using hepatocytes from dog, rat, monkey and man in suspension, comparable results were found in experiments with freshly prepared and cryopreserved hepatocytes when efflux of substrates of MDR1 (ABCRP), BCRP (ABCG2) and MRPs (ABCCs) was measured (Li et al. 2008).
Similar(56)
When polar efflux carriers are present, indicated in green in Figure 4, auxin efflux is augmented with p, such that the total permeability rate becomes (p + q).
When the efflux of KCl was complete, water in the pores reverted to its LDW state.
Similarly, most compounds displayed small increases in accumulation when ABC efflux pumps were inhibited with reserpine.
Recent data on in vitro mutants have suggested that virulence of P. aeruginosa might be reduced when mex efflux systems are overexpressed [ 20].
When the efflux activity of the AcrB variants was plotted against their relative trimer stabilities, the requirement of a threshold stability for function was observed.
Its functional characterization had been described when Cl− efflux was measured upon substituting extracellular sodium (Na+) by N-methyl-D-glucamine (NMDG).
As shown in Figure 7a and b, modules 2, 3, and 6 exhibit better performance (~3 times more responsive than other designs) when the efflux f16 cannot be ignored.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com