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If we wish to ask if organisms are optimally adapted to their environment, we need to infer, from the environment, what optimal phenotypic adaptation would look like.
What optimal means here depends obviously on the choice of a cost function.
Now, it is not anymore so clear what optimal means, that is, there are plenty of objectives to be considered simultaneously.
An interesting question is therefore in what optimal structure is the power-law flow fastest, considering different responses of viscous resistance and capillary force to the structural parameters.
In addition, and standing as a barrier to improvement, it is not certain that there is a universal view of what optimal headache services should look like, or, indeed, of the meaning in this context of "optimal".
Additional data of unconfirmed cargo is shown in Table 4. From the seven confirmed cargoes, ship owner needs to know what optimal (best) cargo mix to select for each ship to fix it, taking into account the three unconfirmed cargoes which might be confirmed later on.
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Our job is not to say whats optimal what is the right thing to do, that's for policy makers.
You might sum it up as classical liberal holism: what is optimal for one must be optimal for all.
However, what is optimal in a simple world may not be optimal in an ecological environment.
To assess the incidence of sub-optimal sedation, it is necessary to consider the definition of what constitutes optimal sedation.
"What's optimal?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com