Sentence examples for what endpoints from inspiring English sources

But for a new chemical entity, knowing what endpoints to measure remains a formidable challenge.

But a significant impediment to these trials remains the question of what endpoints should be measured?

The design of the TAME trial very cleverly skirts around this based on the fact that there are decades of data on metformin in humans, providing unequaled clarity of what endpoints are most likely to yield a positive outcome.

In this paper I outline three possible reasons why this knowledge gap still exists and consider how they could be adopted more broadly, including better considerations about what endpoints should be measured at the initial study design phase.

In addition, while 80-90% of the studies employed rigorous study designs, there were big differences in the number of patients studied, the duration of the studies, and what endpoints were measured to determine benefit.

And, if treated, for how long, with what doses, and to what endpoints?

The main difficulty is that the estimated relative potency (REP) of congeners differs depending on what endpoint is measured, in what tissue and in what animal species.

The next set of summaries capture what endpoint specific information exists namely to address carcinogenicity, repro-developmental, chronic toxicity and acute toxicity endpoints.

So what physiologic endpoints are we trying to manipulate with high-volume CVVH?

What phenotypic endpoints should be used (IC50? LC50? a specific time point?) and how do these relate to tumor pharmacokinetics or pathway activation states?

I just don't think they have a sense yet of what that endpoint is".